5-Amino-1MQ 50mg

$125.00

A small-molecule research material (not a peptide), supplied in a sealed research vial. Subject of pre-clinical investigation in NNMT enzymology research. Batch Certificate of Analysis linked from the QR code on every vial. Research Use Only (RUO). Not for human consumption. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.

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  • ✓ ≥98% HPLC purity standard
  • ✓ Third-party batch COA via QR code on every vial
  • ✓ Reship guarantee — damaged or incorrect orders reshipped at no cost
SKU: YPB.247 Category:

Description

What It Is
A single-component research material supplied for controlled research environments.

Composition
5-amino-1-methylquinolinium (5-amino-1MQ), a small molecule, not a peptide. Supplied in a sealed research vial.

Research Focus (Non-Clinical)
5-amino-1MQ is a membrane-permeable small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme that methylates nicotinamide using S-adenosylmethionine (SAM). In cultured adipocytes, methylquinolinium NNMT inhibitors were associated with reduced intracellular 1-methylnicotinamide (1-MNA), increased intracellular NAD+ and SAM, and suppressed lipogenesis. In the same study, selectivity screening found no inhibition of structurally related SAM-dependent methyltransferases or of NAD+ salvage-pathway enzymes. It is presented here as a reference compound in NNMT enzymology and NAD+/SAM metabolic-flux research. Findings described here are from cell-culture and mouse model systems.

Documentation
Every vial carries a QR code on its label linking to the Certificate of Analysis for its batch, issued by an independent third-party laboratory.

Important Notice
For research use only. Not for human consumption. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.

Quality & Manufacturing
Batch COA linked from the vial label. Tamper-evident seal.

Every vial of this compound carries a QR code on its label linking to the Certificate of Analysis for its batch, issued by an independent third-party laboratory. The certificate reports identity (LC-MS) and HPLC purity for the tested batch, with a verification status you can check.

Want to review a certificate before ordering? Email research@edgepeptideco.com with the product name and we will send the most recent one. How COAs work.

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Supplied as lyophilized (freeze-dried) powder in a sealed, tamper-evident research vial.

  • Store at −20°C, protected from light and moisture, until use.
  • Keep sealed until ready for laboratory use — do not open or reconstitute until immediately before use.
  • Not for human consumption. Not for human or veterinary use.